The Transportation Research Board is part of the National Academies of Sciences, Engineering and Medicine. In an exclusive interview with TRB Executive Director Neil Pedersen—we learn about some of the critical issues in transportation that are being spotlighted this year for special attention by the TRB Executive Committee. The three issues at the top of the list are Transformational Technologies, Resilience and Public Health. Transportation scholars want to know, what research needs to be done today to prepare America for the evolution of connected and autonomous vehicles; environmental concerns; and health issues related to transportation. Pedersen addresses those issues and he discusses his concerns about whether America is investing enough in transportation research.